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New report published

New report reviewing earlier Irish data into association between Pandemrix and Narcolepsy published A new report has been published entitled “INVESTIGATION OF AN ASSOCIATION BETWEEN ONSET OF NARCOLEPSY AND VACCINATION WITH PANDEMIC INFLUENZA VACCINE, IRELAND APRIL 2009-DECEMBER 2010“. This appears to be a thorough review of the original case data. It reiterates what it describes as “the crude association between Pandemrix vaccination and narcolepsy as observed in Finland and Sweden”. It states that the relative risk of children/adolescents developing Narcolepsy after having Pandemrix is 13.9 times higher than those who did not have this vaccination. The report can be found in full here. The Journal has picked up on the story today. Click here to read the article.

By |September 28th, 2015|Categories: Public Posts|0 Comments

New peer reviewed research “provide a link between Pandemrix and narcolepsy”

A new peer reviewed research article has been published in PLOS ONE titled "Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines: Implications for Pandemrix-Associated Narcolepsy Risk".  (click the link to read the full article) The article compares two GlaxoSmithKline manufactured H1N1 swine flu vaccines, both of which used the AS03 adjuvant.  Arepanrix, produced by GSK in Canada and Pandemrix produced by GSK in Europe. The article concludes: "This work identified 1) higher amounts of structurally altered viral NP* in Pandemrix than in Arepanrix, 2) detergent-induced antigenic changes of viral NP, that are recognized by antibodies from children with narcolepsy, and 3) increased antibody response to NP in association of DQB1*06:02 risk allele of narcolepsy. These findings provide a link between Pandemrix and narcolepsy. Although detailed mechanisms of [...]

New report reviewing earlier Irish data into association between Pandemrix and Narcolepsy published

A new report has been published entitled "INVESTIGATION OF AN ASSOCIATION BETWEEN ONSET OF NARCOLEPSY AND VACCINATION WITH PANDEMIC INFLUENZA VACCINE, IRELAND APRIL 2009-DECEMBER 2010". This appears to be a thorough review of the original case data.  It reiterates what it describes as "the crude association between Pandemrix vaccination and narcolepsy as observed in Finland and Sweden".  It states that the relative risk of children/adolescents developing Narcolepsy after having Pandemrix is 13.9 times higher than those who did not have this vaccination. The report can be found in full here. The Journal has picked up on the story today. Click here to read the article.  

By |May 3rd, 2014|Categories: Media, Science|Tags: , , , |0 Comments
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